A product that is manufactured in a bioreactor or a
fermentor, is recovered and purified in several subsequent unit
operations. The economy of a manufacturing process is determined by
the cost effectiveness of these downstream operations. This course
discusses these operations and the basic underlying principles with
worked out problems. This course will be useful for UG/PG students
in biotechnology/chemical engineering as well as practicing
bioprocess and chemical engineers.
Solid Liquid Separation,Pre-treatment and
Filters/centrifuge,Liquid-Liquid Extraction,Liquid-Liquid
extraction (continued)
3.
Adsorption,Reversed micellar and aqueous two phase
extraction,Membranes,Membranes (continued)
4.
Precipitation and crystallization,Product stabilization,
drying, Lyophilisation,Electrophoresis / SDS
PAGE,Chromatography, Chromatography
(continued),Chromatography (continued),Chromatography
(continued),Future trends, Other downstream
operations/Summary of the course
Basics of physics/chemistry/Maths, Mass and heat balance, and thermodynamics
Revise and read books pertaining to down stream processing. Listen to my NPTEL -- 40 hrs lectures"Â
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