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Course Co-ordinated by IISc Bangalore
Dr. J.R. Mudakavi
IISc Bangalore


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In this course, we will introduce techniques to analyze dynamics of evolving microbial populations. The topics we will look to cover are as follows. 1.Introduction to Evolution and population dynamics; 2.Fitness Landscape and Sequence Spaces; 3.Evolutionary Game Theory (fitness dependent on frequency); 4.Origin of Cooperation (genes to genomes; single-cell to multicellular organisms); 5.Deterministic and Stochastic Description of Finite Populations; 6.Evolutionary Graph Theory; 7.Modeling Infinite Populations; 8.Examples: Analysis of evolution of Virulence, Cancer, and HIV. All biology student (with basic XI and XII standard biology) interested in learning development of models, and all students from engineering/physics/chemistry background but passionate about learning modeling of biological processes will benefit from the course.

Module Name
Module 1 Introduction to the subject and class overview.
Module 2 What is evolution?
Module 3 Mechanisms of evolution of microbial populations.
Module 4 Microbial Evolution Experiments
Module 5 Evolutionary Games (game theory in evolution)
Module 6 Evolution in finite populations
Module 7 Evolutionary Graph Theory
Module 8 Distribution of beneficial, deleterious, and neutral mutations.
Module 9 Evolution of virulence
Module 10 Critical transitions and ecosystem stability


1) Atomic absorption spectrometry Bernhard Welz, VCH publication,1983.
2) Instrumental methods of analysis seventh edition Willard, Merritt, Dean, Settle: CBS publishers, New Delhi, -1986.
3) Instrumental analysis Skoog, Holler, Crouch, Cengage Learning India Private Limited, 2007



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