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Course Co-ordinated by IISc Bangalore
Coordinators
 
Prof. Hanudatta S. Atreya
IISc Bangalore

 

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The objective of the course is to teach the basic aspects of nuclear magnetic resonance (NMR) spectroscopy, which is an important analytical tool in chemical and pharmaceutial industry for structural characterization of molecules.

The topics to be covered will include one-dimensional NMR, Chemical shifts, J-coupling, Interpretation of 1D NMR spectrum, Basics of 2D NMR, Different 2D NMR experiments and their application/interpretation, Application of 2D NMR for assignment of molecules and peptides.

Week

Topic/s

1

Introduction to NMR spectroscopy

2

Chemical shifts and J-coupling

3

One-dimensional proton NMR

4

One dimensional NMR of X-nuclei (13C, 15N, 31P and 19F)

5

Homonuclear 2D NMR

6

Heteronucler 2D NMR

7

Structure determination of molecules

8

Advanced topics (Solvent suppression, Drug Discovery, DOSY)

Should have studied Chemistry at undergraduate level and Mathematics at least up to 12th Standard


  1. Basic One and Two Dimensional NMR: by Horst Fiebrolin.
  2. NMR Spectroscopy Explained: by Neil Jacobsen
  3. Understanding NMR spectroscopy: by James Keeler
  4. Introduction to Spectroscopy: by Pavia et al.


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